NMO parallels MS in that it can beР’В a relapsing-remitting disease. We used to think NMO was just a special type of MS, but now we know theyРІР‚в„ўre different and we treat them differently. This helps to see if there is any swelling in the retina and if Central Serious Chorioretinopathy is present.Р”Р„lso known as DevicРІР‚в„ўs disease,Р’В NMOР’В is an autoimmune disorder affecting theР’В optic nerves and the spinal cord. Vitamin B12 deficiency is ruled out through a blood test.Р”В¬entral Serous Chorioretinopathy is an eye disease where fluid is leaked under the retina and causes loss of vision in one eye.Р’В Even if we think a patient has MS, we always perform Optical Coherence Tomography on patients with sudden or pretty rapid visual loss. When your body doesnРІР‚в„ўt get enough Vitamin B12, serious conditions such as vision loss, fatigue and muscle weakness, lack of bladder control, and depression can occur. Vitamin B12Р’В is responsible for a lot ofР’В important functions for your body, such as making your red blood cells and your DNA, and helping make neurotransmitters in your brain. Sarcoid is usually ruled out by biopsy or taking a tissue sample. Just like MS, Sarcoidosis affects women more than men and is found most frequently in people 20 РІР‚вЂњ 40 years old. These include vision loss,Р’В depression, tender joints, numbness, and bladder changes. But sarcoid can affect the brain, resulting in several neurological symptoms similar to MS. It usually starts in the lungs, and the lymph nodes that drain the lungs become enlarged. Sarcoidosis is an inflammatory disease with an unknown cause.

Lupus is usually ruled out by blood tests. And in very rare cases, a person can have both diseases. However, not everyone suffering from Lupus experiences the rashР’В immediately - resulting in a disease that sometimes starts out very similarly to MS. Lupus stands out from MS with itРІР‚в„ўs most commonР’В symptom-Р’В a rash on the face that resembles a butterfly.

They share several symptoms such as fatigue, pain, and headaches. Both are diseases of the immune systemР’В andР’В affect women more than men. Since both the MRI findings and symptoms overlap in MS and Hypermobility Syndromes, Hypermobility Syndromes can be mistaken for MS and should be considered in the differential diagnosis. After comparing MRIs of patients with hypermobility to those of MS patients, we found White Matter Lesions in similar locations of both. Through recent research, we have found that patients with hypermobility syndromes share similar symptoms to MS Patients. The Diseases that Mimic Multiple Sclerosis (MS)Р”В«enign Hypermobility Syndrome affects perhaps 5% of the population and is causedР’В by joints that are РІР‚Сљoverly stretchyРІР‚Сњ or more flexible than normal.Р’В It is associated with symptoms such as autoimmune disease, headache, joint pain, fatigue/sleep problems, dysautonomia, and cardiac abnormalities.

Therefore, if anything is amiss about the symptoms or signs you are experiencing, and arenРІР‚в„ўt consistent with the imaging findings typical of Multiple Sclerosis, then other diseases need to be looked for. But, despite many of the symptoms being the same, these mimicking diseases donРІР‚в„ўt have the typical brain and spinal cord MRI findings of Multiple Sclerosis. One reason for thisР’В misdiagnosis is theР’В many other diseases that affect people in the same age groupР’В withР’В symptoms that overlap with those of MS. They have a few РІР‚СљspotsРІР‚Сњ on their brain MRI, but they arenРІР‚в„ўt actuallyР’В spotsР’В typical of MS. They are experiencing overwhelming fatigue and hand numbness, but it actually turns out to be sleep apnea and carpal tunnel syndrome or a pinched nerve in the neck. They are already on MS medications, butР’В donРІР‚в„ўt really have MS. Yet, even with the improvement in MS diagnosis,Р’В each year I still see 8-10 patients who have been diagnosed with MS and come toР’В me looking for second or РІР‚Сљn-thРІР‚Сњ opinions. With the adoption of newР’В diagnostic criteria, such asР’В the MacDonald 2010 Criteria, mostР’В majorР’В MS centers around the country have been able to diagnose MS with more certainty. For a long time, Multiple Sclerosis (MS) has been diagnosed byР’В exclusion of other possible diseases.

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